The interviewer is not interested in hearing about all of your insecurities and weaknesses. Instead, share with her a change that could be seen as a positive. That way,when the "what would you change" question comes up, you can pick something not particularly relevant to the role. For example, it's best not to say you wish you could have a steadier hand if you're applying to be a decorator. But you could suggest that you're not good at public speaking if it's a skill rarely required of someone in your target profession. Be honest and attempt to appear flexible, but ensure you make an impression that accurately reflects your goals, skills and limitations.